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1.
BMC Res Notes ; 5: 223, 2012 Jul 02.
Artigo em Inglês | MEDLINE | ID: mdl-22571506

RESUMO

Scientific progress is driven by the availability of information, which makes it essential that data be broadly, easily and rapidly accessible to researchers in every field. In addition to being good scientific practice, provision of supporting data in a convenient way increases experimental transparency and improves research efficiency by reducing unnecessary duplication of experiments. There are, however, serious constraints that limit extensive data dissemination. One such constraint is that, despite providing a major foundation of data to the advantage of entire community, data producers rarely receive the credit they deserve for the substantial amount of time and effort they spend creating these resources. In this regard, a formal system that provides recognition for data producers would serve to incentivize them to share more of their data. The process of data citation, in which the data themselves are cited and referenced in journal articles as persistently identifiable bibliographic entities, is a potential way to properly acknowledge data output. The recent publication of several sorghum genomes in Genome Biology is a notable first example of good data citation practice in the field of genomics and demonstrates the practicalities and formatting required for doing so. It also illustrates how effective use of persistent identifiers can augment the submission of data to the current standard scientific repositories.


Assuntos
Genoma de Planta/genética , Genômica/métodos , Disseminação de Informação/métodos , Sistemas de Informação/estatística & dados numéricos , Sorghum/genética , Genômica/normas , Serviços de Informação/normas , Serviços de Informação/estatística & dados numéricos , Sistemas de Informação/normas , Editoração/normas , Editoração/estatística & dados numéricos
2.
Gigascience ; 1(1): 1, 2012 Jul 12.
Artigo em Inglês | MEDLINE | ID: mdl-23587310

RESUMO

We are delighted to announce the launch of GigaScience, an online open-access journal that focuses on research using or producing large datasets in all areas of biological and biomedical sciences. GigaScience is a new type of journal that provides standard scientific publishing linked directly to a database that hosts all the relevant data. The primary goals for the journal, detailed in this editorial, are to promote more rapid data release, broader use and reuse of data, improved reproducibility of results, and direct, easy access between analyses and their data. Direct and permanent connections of scientific analyses and their data (achieved by assigning all hosted data a citable DOI) will enable better analysis and deeper interpretation of the data in the future.

3.
Curr Opin Neurobiol ; 16(2): 213-21, 2006 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-16563734

RESUMO

The neural substrate of sequence learning is well known. However, we lack a clear understanding of the detailed functional properties of many of the areas involved. The reason for this discrepancy lies, in part, in the fact that two types of processes, implicit and explicit, subserve motor sequence learning, and these often interact with each other. The most significant recent advances have been the elucidation of the very complex relationships between medial motor areas and the temporal and ordinal control of sequences, and the demonstration that motor cortex is an important site for sequence storage and production. The challenge for the future will be to develop a coherent and internally consistent theory of sequence control.


Assuntos
Córtex Cerebral/fisiologia , Aprendizagem/fisiologia , Destreza Motora/fisiologia , Movimento/fisiologia , Animais , Humanos , Memória de Curto Prazo/fisiologia , Córtex Motor/fisiologia , Rede Nervosa/fisiologia , Neuropsicologia/tendências , Córtex Pré-Frontal/fisiologia
4.
Magn Reson Imaging ; 23(5): 647-51, 2005 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16051039

RESUMO

This project was designed to assess whether MRI imaging could detect Lorentz-force-induced motion in conductive samples. Experiments were performed by applying alternating voltages across 2% agar and 18% bovine gels placed in the field of a 1.5-T MRI scanner. Motion-sensitized time-gated MRI images that were obtained and analyzed with custom-developed software used in previous studies revealed the production of movement in both agar and gel samples. Motion was most pronounced in the plane vertical to the sample and had the greatest amplitude when the current path was perpendicular to the scanner's magnetic field. These findings are compatible with the vector cross product nature of the Lorentz force and suggest that the imaging of Lorentz-force-induced motion in conductive samples is feasible. Whether this approach can be extended to study electrically active tissues such as the peripheral nerves, brain and heart remains to be seen.


Assuntos
Imageamento por Ressonância Magnética/métodos , Géis , Movimento (Física) , Imagens de Fantasmas , Software
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